Fig. 3
Effects of SK, 4-OHT, and the combination on decreasing the mitochondrial membrane potential of cells. a Flow cytometry analysis of MCF-7 cells with high Δѱm (%) by JC-1 staining. b Statistic analysis of MCF-7 cells with low Δѱm (%) (percentage of cells in Q3). c The representative image of PI staining of MCF-7 cells. d Flow cytometry analysis of MDA-MB-435S cells with high Δѱm (%) by JC-1 staining. e Statistic analysis of MDA-MB-435S cells with low Δѱm (%) (percentage of cells in Q3). f The representative image of PI staining of MDA-MB-435S. Data are mean ± S.E.M. from three independent experiments (**P < 0.01 compared with the negative control; ##P < 0.01 compared with the combination group)