Fig. 5

The inhibitory effect of SCU administration on tumor growth in nude mice in vivo. a The morphology of tumor in nude mice after the administration of DMSO (control) and 25 mg/kg 5-FU as well as 50 mg/kg, 150 mg/kg and 300 mg/kg SCU. Scale bar = 1 cm. PET-CT assay of tumor size in b control, c Scu-50 mg/kg, d Scu-150 mg/kg and e Scu-300 mg/kg groups. f Variation of ponderal growth in control, 5-FU, Scu-50 mg/kg, Scu-50 mg/kg and Scu-50 mg/kg groups from 2 d to 20 days. g The relative weight of tumor in nude mice after the administration of DMSO (control) and 25 mg/kg 5-FU as well as SCU with 50 mg/kg, 150 mg/kg and 300 mg/kg. h The relative volume changes of tumor after the administration of DMSO (control) and 25 mg/kg 5-FU as well as SCU with 50 mg/kg, 150 mg/kg and 300 mg/kg at 3, 6, 9, 12, 15, 18 d. Con: Control; 5-FU: 5-Fluorouracil; SCU, Scutellarin; d, day. All data are shown as mean ± SD, n = 10, *p < 0.05; **p < 0.01