Fig. 6

Ingenuity pathway analysis of genes function in RKO cells. The concentration of a AST and ALT, b HGB as well as c WBC and PLT in control, 5-FU as well as SCU with 50 mg/kg, 150 mg/kg and 300 mg/kg. All data are shown as mean ± SD, n = 4/group. d Disease and function bar graph of differentially expressed genes in classification of diseases. e The heat maps of relationship between upregulated and downregulated genes in activation or inhibition of diseases. The orange stands for z-score > 0; the blue stands for z-score < 0; the gray means no Z-score value. Con control, 5-FU 5-fluorouracil, Scu scutellarin, d day, HGB hemoglobin, AST aspartate aminotransferase, ALT alanine transaminase, WBC white blood cell, PLT platelet