Fig. 2
From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease
Changes of zo-1 level enzymes before AD onset in APP/PS1 mice. a Western blot revealed that zo-1 level was enhanced in the hippocampus of APP/PS1 mice compared to WT at 2- and 3-month old, whereas zo-1 expression level decreased in 5- and 6-month old APP/PS1 mice compared to age-match WT mice *P < 0.05; n = 3 per group). b Western blot revealed that zo-1 level was enhanced in the cortex of APP/PS1 mice compared to WT at 2- and 3-month old, whereas zo-1 expression level decreased in 5- and 6-month old APP/PS1 mice compared to age-match WT mice (*P < 0.05, **P < 0.01; n = 3 per group)