Fig. 5
From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease
FO treatment inhibited NF-κB activation in both the hippocampus and cortex region of the APP/PS1 mice. a Representative images of Western blot analysis on the expression of phosphorylated p65 (p-p65, Ser536) and total p65 in the hippocampus region of the 5-month old APP/PS1 mice treated with FO or CO for 4 weeks and the age-matched WT mice (normal control). b Representative images of Western blot analysis on the expression of phosphorylated p65 (p-p65, Ser536) and total p65 in the cortex region of the 5-month old APP/PS1 mice treated with FO or CO for 4 weeks and the age-matched WT mice (normal control). c Quantification analysis revealed that FO treatment significantly suppressed the NF-κB activation found in APP/PS1 mice (*P < 0.05, **P < 0.01; n = 5 per group)