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Table 1 Profiles of polyunsaturated fatty acids in the hippocampus from fish oil-treated mice and the control mice with corn oil treatment (n = 3 per group)

From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease

Fatty acidHippocampus
Corn oil-miceFish oil-mice
ω-6 PUFA
 LA (C18:2 ω-6)0.91 ± 0.020.91 ± 0.05
 EDA (C20:2 ω-6)0.27 ± 0.050.24 ± 0.03
 DGLA (C20:3 ω-6)0.51 ± 0.030.47 ± 0.05
 AA (C20:4 ω-6)13.91 ± 0.4211.11 ± 1.02*
 DTA (C22:4 ω-6)4.26 ± 0.173.99 ± 0.21
 n-6 DPA (C22:5 ω-6)4.91 ± 0.431.26 ± 0.33***
 Total28.05 ± 1.1218.41 ± 1.16*
ω-3 PUFA
 ω-3 DPA (C22:5 ω-3)0.15 ± 0.010.39 ± 0.03**
 DHA (C22:6 ω-3)16.12 ± 1.8927.18 ± 2.25**
 Total16.57 ± 0.4426.52 ± 1.21**
Total PUFA35.75 ± 1.5943.01 ± 1.73*
ω-6/ω-31.56 ± 0.060.68 ± 0.06**
  1. Data expressed as mol% of total fatty acids ± SEM (*P < 0.05; **P < 0.01; ***P < 0.001). AA arachidonic acid, DGLA dihomo-γ-linolenic acid, DHA docosahexaenoic acid, DPA docosapentaenoic acid, DTA docosatetraenoic acid, EDA eicosadienoic acid, LA linoleic acid, MUFA monounsaturated fatty acids (the value is given as follows: C16:1 + C18:1 + C20:1 + C22:1), SFA saturated fatty acids(the value is given as follows: C14:0 + C15:0 + C16:0 + C17:0 + C18:0 + C20:0 + C22:0 + C24:0); PUFA polyunsaturated fatty acids