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Table 1 Characteristics of TCM Pathogenesis in NCP and SARS

From: Treatment efficacy analysis of traditional Chinese medicine for novel coronavirus pneumonia (COVID-19): an empirical study from Wuhan, Hubei Province, China

 NCP (COVID-19)SARS
Original areaWuhan, HubeiFoshan, Guangdong
Onset timeNov, 2019Nov, 2002
TCM pathogenDampness toxinEpidemic toxin (疫毒)
Main symptomsLow fever or no fever, some patients only felt fatigue, or dry cough, nausea, diarrhea. Severe dyspnea occurs 1 week later, which can lead to multiple organs failure.The typical symptom is fever (frequent high fever), following fatigue, head and muscle pain. Some patients present dry cough, less sputum after 3 to 6 days, as well as chest discomfort and wheezing. In severe stage, the occurrence of gasp and acute respiratory distress.
Location of diseaseLungs, involving spleen and stomach, eventually affecting heart, liver and kidneyMainly in lung
Pathological evolutional periods1 Medical observation period: fatigue and gastrointestinal dysfunction or fever
2 Clinical period when diagnosed
2.1 Mild type: syndrome of cold dampness obstructing lung (寒湿郁肺), syndrome of lung with dampness heat retention (湿热蕴肺证)
2.2 Moderate type: syndrome of lung with dampness toxin retention (湿毒郁肺证), syndrome of cold dampness blocking lung (寒湿阻肺证)
2.3 Severe type: syndrome of pestilent toxin blocking lung (疫毒闭肺证), syndrome of dual blaze of Qi and blood (气血两燔证)
2.4 Critical type: syndrome of internal block and external collapse (内闭外脱证)
3 Recovery period: syndrome of Qi and Yin deficiency in lung and spleen (肺脾气阴两虚证)
1 Early stage: syndrome of epidemic toxin invading lung (疫毒犯肺证)
2 Progressive stage: syndrome of epidemic toxin obstructing lung (疫毒壅肺), syndrome of blocking lung with severe dyspnea (肺闭喘憋), syndrome of internal block and external collapse (内闭外脱证)
3 Recovery period: syndrome of Qi and Yin deficiency (气阴两虚证), syndrome of phlegm and blood stasis blocking collaterals (痰瘀阻络证).