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Table 1 The demographic and clinical characteristics of RA patients at baseline in the full analysis set

From: Traditional Chinese medicine Biqi capsule compared with leflunomide in combination with methotrexate in patients with rheumatoid arthritis: a randomized controlled trial

Characteristics

MTX + Biqi (n = 35)

MTX + LEF (n = 35)

P value

Age (SD), years

42.74 (10.35)

44.40 (11.36)

0.526

Female, n (%)

32 (91.43)

31 (88.57)

0.690

Disease duration (SD), months

26.12 (31.46)

35.19 (33.45)

0.136

TJC (SD), n

8.97 (6.31)

8.29 (6.42)

0.544

SJC (SD), n

6.03 (5.34)

4.23 (3.03)

0.246

Patient’s assessment of pain (SD), mm

58.57 (24.54)

56.29 (21.43)

0.678

PhGADA†(SD), mm

52.09 (25.53)

52.00 (20.37)

1.000

PaGADA†(SD), mm

55.71 (25.61)

53.00 (20.37)

0.673

Morning stiffness (SD), min

69.00 (53.99)

56.03 (49.06)

0.365

HAQ, mean ± SD

1.02 (0.81)

0.73 (0.73)

0.116

hs-CRP (SD), mg/L

12.45 (18.76)

15.88 (17.27)

0.259

ESR (SD), mm/h

44.49 (27.20)

54.86 (27.13)

0.115

RF# (SD), U/mL

153.55 (162.72)

174.33 (183.97)

0.787

Anti-CCP#, positive rate

28 (84.85)

29 (82.86)

1.000

DAS28 (SD)

4.66 (1.39)

4.55 (1.22)

0.742

NSAIDs, n (%)

29 (82.9%)

28 (80.0%)

0.759

Glucocorticoid oral, n (%)

6 (20.0%)

14 (37.1%)

0.112

Folic acid tablet, n (%)

23 (65.7%)

27 (77.1%)

0.290

Antacids, n (%)

27 (77.1%)

26 (74.3%)

0.780

  1. Data are presented as the mean (SD) or n (%)
  2. TJC tender joint count, SJC swollen joint count, PaGADA patient’s global assessment of disease activity, PhGADA physician’s global assessment of disease activity, HAQ Health Assessment Questionnaire, ESR erythrocyte sedimentation rate, CRP C-reactive protein, RF rheumatoid factor, anti-CCP anti-cyclic citrullinated peptide antibody, DAS28 28-joint disease activity score, cDAI clinical disease activity index
  3. RF# was measured by immunonephelometry with a cut-off value of 20 U/mL. Anti-CCP# was measured using a commercially available second-generation ELISA kit (Abbott, USA) with a cut-off value of 25 U/mL
  4. †Measured on a 100-mm visual analog scale. NSAID: nonsteroidal anti-inflammatory drug