Group | Dose (mg/kg) | Catalase level (kU/I) | TBARS Level (nM/100 g) | GSH (µg/mg) | |||
---|---|---|---|---|---|---|---|
Predose | 8th week | Predose | 8th week | Predose | 8th week | ||
NC | – | 30.77 ± 1.66 | 30.20 ± 1.44 | 0.73 ± 0.02 | 0.75 ± 0.02 | 64.40 ± 1.10 | 64.83 ± 1.50 |
DC | – | 21.28 ± 1.20 | 19.82 ± 1.48 | 1.15 ± 0.02 | 3.60 ± 0.03 | 57.30 ± 1.70 | 47.72 ± 1.40 |
GBa | 5 | 21.42 ± 1.11 | 22.17 ± 1.36 | 1.17 ± 0.02 | 1.78 ± 0.04 | 56.70 ± 1.60 | 56.53 ± 1.50 |
FOa | 50 | 21.66 ± 1.44 | 35.50 ± 1.25* | 0.98 ± 0.01 | 0.58 ± 0.02* | 59.90 ± 1.50 | 64.9 ± 1.50* |
FOa | 100 | 21.98 ± 1.23 | 37.80 ± 1.43* | 1.02 ± 0.01 | 0.56 ± 0.03* | 59.00 ± 1.60 | 65.11 ± 1.30* |
FOa | 200 | 21.85 ± 1.55 | 40.50 ± 1.37* | 1.00 ± 0.02 | 0.54 ± 0.04* | 61.58 ± 1.30 | 65.50 ± 1.40* |
ARFa | 15 | 22.19 ± 1.15 | 38.65 ± 1.55* | 0.97 ± 0.02 | 0.53 ± 0.01* | 60.98 ± 1.40 | 65.55 ± 1.40* |
ARFa | 30 | 21.28 ± 1.78 | 39.56 ± 1.70* | 1.00 ± 0.02 | 0.45 ± 0.01* | 62.85 ± 1.20 | 66.50 ± 1.10* |
ARFa | 60 | 22.49 ± 1.57 | 43.65 ± 1.31* | 0.96 ± 0.01 | 0.40 ± 0.02* | 62.11 ± 1.30 | 70.50 ± 1.10* |
Stya | 7.5 | 21.42 ± 1.25 | 30.50 ± 1.45* | 1.15 ± 0.02 | 0.97 ± 0.03* | 60.60 ± 1.20 | 59.34 ± 1.30* |
Stya | 15 | 21.29 ± 1.11 | 32.50 ± 1.34* | 1.02 ± 0.02 | 0.95 ± 0.03* | 61.83 ± 1.50 | 59.90 ± 1.40* |
Stya | 30 | 21.89 ± 1.45 | 33.65 ± 1.05* | 0.97 ± 0.01 | 0.93 ± 0.01* | 60.13 ± 1.70 | 60.11 ± 1.50* |
Sana | 7.5 | 22.29 ± 1.15 | 31.52 ± 1.13* | 1.00 ± 0.03 | 0.93 ± 0.03* | 59.75 ± 1.60 | 60.22 ± 1.80* |
Sana | 15 | 21.28 ± 1.18 | 31.59 ± 1.56* | 1.02 ± 0.02 | 0.89 ± 0.02* | 61.74 ± 1.20 | 60.25 ± 1.90* |
Sana | 30 | 22.51 ± 1.16 | 32.90 ± 1.50* | 0.98 ± 0.01 | 0.85 ± 0.02* | 61.17 ± 1.50 | 61.44 ± 1.70* |
Nio 1a | 60 | 22.70 ± 1.78 | 37.56 ± 1.77* | 0.92 ± 0.02 | 0.45 ± 0.02* | 59.66 ± 1.40 | 63.22 ± 1.40* |
Nio 2a | 60 | 22.90 ± 1.34 | 46.25 ± 1.45* | 1.22 ± 0.02 | 0.34 ± 0.02* | 59.77 ± 1.21 | 75.55 ± 1.10* |
Nio 3a | 60 | 21.97 ± 1.56 | 39.56 ± 1.33* | 0.89 ± 0.01 | 0.46 ± 0.02* | 59.34 ± 1.33 | 65.66 ± 1.10* |
Nio 4a | 60 | 22.56 ± 1.77 | 33.58 ± 1.45* | 0.94 ± 0.02 | 0.50 ± 0.01* | 59.83 ± 1.54 | 62.99 ± 1.40* |
Nio 5a | 60 | 22.89 ± 1.44 | 35.65 ± 1.55* | 1.01 ± 0.01 | 0.48 ± 0.02* | 60.13 ± 1.70 | 65.55 ± 1.30* |
Nio 6a | 60 | 22.48 ± 1.35 | 34.60 ± 1.45* | 0.90 ± 0.01 | 0.56 ± 0.01* | 60.75 ± 1.55 | 63.88 ± 1.40* |
Placebo Ia | – | 22.45 ± 1.33 | 20.22 ± 1.22 | 1.11 ± 0.01 | 1.30 ± 0.04 | 62.98 ± 1.40 | 60.00 ± 1.30* |
Placebo IIa | – | 22.56 ± 1.77 | 19.20 ± 1.46 | 1.22 ± 0.02 | 1.45 ± 0.04 | 62.55 ± 1.41 | 59.33 ± 1.20* |