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Table 3 Major chemical constituents and possible targets of TCM in COVID-19

From: The potential insights of Traditional Chinese Medicine on treatment of COVID-19

 

Major chemical constituents

Possible targets

References

HXZQ

Quercetin, isorhamnetin, irisolidone, kaempferol, wogonin, baicalein

PTGS2, HSP90AB1, CAMSAP2

[5, 6]

LHQW

Kaempferol, quercetin, glycyrrhetinic acid, stigmasterol, indigo

SARS-CoV-2 3CL (Mpro), ACE2, MAPK, PI3K-AKT, NF-κB

[8]

SFJD

Quercetin, kaempferol, luteolin

IL-6, ALB, MAPK3

[18]

XBJ

Hydroxysafflor yellow A, chlorogenic acid, salvianolic acid B

NF-κB, HIF-1, VEGF

[21]