Skip to main content

Table 3 IC50, CC50 and selectivity indices of porcupine dates extracts and tannic acids against DENV-2 in Vero cells

From: Anti-dengue virus serotype 2 activity of tannins from porcupine dates

Sample

CC50 (µg/mL)

IC50 (µg/mL)b

Selectivity index (SI)c

MBD

NCa

101 ± 10d

> 2

MPD

NCa

107 ± 24

> 2

BDTF

> 164

25 ± 7

> 7

PDTF

> 164

11 ± 3

> 15

FT

> 200

18 ± 15

> 11

ST

196

26 ± 8

8

  1. aNC: No cytotoxicity at all concentration up to 200 µg/mL tested against Vero cells
  2. bEach value represents the mean ± SD of two independent experiments performed in duplicate
  3. cSelectivity index was calculated by dividing CC50 by IC50
  4. dIC50 of MBD may not be accurate as it was not in a dose-dependent manner. It was estimated from the plot of the percentage of virus yield reduction against the extract’s concentrations of 50 and 200 μg/mL, by using linear regression