Sample | CC50 (µg/mL) | IC50 (µg/mL)b | Selectivity index (SI)c |
---|
MBD | NCa | 101 ± 10d | > 2 |
MPD | NCa | 107 ± 24 | > 2 |
BDTF | > 164 | 25 ± 7 | > 7 |
PDTF | > 164 | 11 ± 3 | > 15 |
FT | > 200 | 18 ± 15 | > 11 |
ST | 196 | 26 ± 8 | 8 |
- aNC: No cytotoxicity at all concentration up to 200 µg/mL tested against Vero cells
- bEach value represents the mean ± SD of two independent experiments performed in duplicate
- cSelectivity index was calculated by dividing CC50 by IC50
- dIC50 of MBD may not be accurate as it was not in a dose-dependent manner. It was estimated from the plot of the percentage of virus yield reduction against the extract’s concentrations of 50 and 200 μg/mL, by using linear regression