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Fig. 3 | Chinese Medicine

Fig. 3

From: Transcriptomics- and metabolomics-based integration analyses revealed the potential pharmacological effects and functional pattern of in vivo Radix Paeoniae Alba administration

Fig. 3

Integrated analyses of the liver revealed that it was the site where RPA exerted a major effect. a RPA induced a number of upregulated genes (red) and downregulated genes (blue) in various vital organs (p ˂ 0.05, cutoff = 1.5). b Number of pathways enriched with DEGs in each organ, based on KEGG. c Three-dimensional PCA revealed the overall intergroup separation of the liver transcriptomes. d Volcano plot showing the upregulated genes (red) and downregulated genes (blue) in liver tissue. e Venn diagram showing the overlapping pathways enriched with DEGs from our results and previously identified targets of RPA in the TCMSP. f Venn diagram showing the overlapping pathways enriched with DEGs by GSEA. Detailed result diagrams are shown in additional files

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Chinese Medicine

ISSN: 1749-8546

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