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Fig. 5 | Chinese Medicine

Fig. 5

From: Transcriptomics- and metabolomics-based integration analyses revealed the potential pharmacological effects and functional pattern of in vivo Radix Paeoniae Alba administration

Fig. 5

RPA had a significant effect on the transcriptome of brain tissue. a Three-dimensional PCA revealed the overall intergroup separation of the brain transcriptomes. b Volcano plot showing the upregulated genes (red) and downregulated genes (blue) in brain tissue. cKEGG enrichment bubble plot of DEGs in the brain transcriptomes (pathway p ˂ 0.05). d Target genes were significantly upregulated (red) and downregulated (blue) by RPA in the neuroactive ligand-receptor interaction pathway. e Venn diagram showing the potential targets of RPA on the cocaine addiction model based on RNA-seq data obtained from the GEO database

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Chinese Medicine

ISSN: 1749-8546

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