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Fig. 4 | Chinese Medicine

Fig. 4

From: Insight into norcantharidin, a small-molecule synthetic compound with potential multi-target anticancer activities

Fig. 4

Underlying regulatory targets of NCTD against invasion and metastasis. NCTD: norcantharidin; YAP: Yes-associated protein; ERK: extracellular regulated protein kinases; Ets1: E-Twenty-Six-1; Sp1: specificity protein 1; STAT1: signal transducers and activators of transcription 1; MMPs: matrix metalloproteinases; EMT: epithelial–mesenchymal transition. (−): Inhibition; (+): Promotion or inducing

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