Skip to main content
Fig. 5 | Chinese Medicine

Fig. 5

From: Insight into norcantharidin, a small-molecule synthetic compound with potential multi-target anticancer activities

Fig. 5

The “more targets” mechanisms of NCTD against tumor vascularization (angiogeneses, VM and lymphangiogenesis). NCTD: norcantharidin; TSP: thrombospondin; Ang-2: angiogenin-2; VEGF: vascular endothelial growth factor; VEGFR: vascular endothelial growth factor receptor; EphA2: ephrin type a receptor 2; FAK: focal adhesion kinase; PI3-K: phosphatidylinositol 3-kinase; MMPs: matrix metalloproteinases; Ln-5γ2: laminin 5γ2; TIMP: tissue metalloproteinase inhibitor. (−): Inhibition; (+): Promotion or inducing

Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us