Fig. 1

Gene expression and transcription levels of inflammasome sensors in the HNSCC patients. a Oncomine analysis of the transcription levels of 12 inflammasome molecules in different types of cancers. This figure indicates the numbers of datasets with statistically significant inflammasome mRNA upregulation (red) or downregulation (blue) in different types of cancers versus the corresponding normal tissues (Threshold settings: P value, 0.05; fold change, 2; gene rank, top 10%). The numbers in the colored cells represent the numbers of dataset meeting the threshold. b, c Different expressions of these inflammasome molecules between tumor and adjacent normal tissues from HNSCC in the GEPIA database. ‘*’ indicates statistical significance with P < 0.05. T tumor, N normal