Fig. 7From: RalB degradation by dihydroartemisinin induces autophagy and IFI16/caspase-1 inflammasome depression in the human laryngeal squamous cell carcinomaThe model of the crosstalk between IFI16/caspase-1 inflammasome and autophagy by DHA in the human laryngeal squamous cell carcinoma. Mechanically, DHA triggered autophagy. Meanwhile, autophagy reduced the expression of RalB and USP33. Furthermore, DHA promoted autophagy, which suppressed the activation of IFI16 inflammasome and the secretion of IL-1βBack to article page