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Fig. 2 | Chinese Medicine

Fig. 2

From: Cryptotanshinone attenuates the stemness of non-small cell lung cancer cells via promoting TAZ translocation from nuclear to cytoplasm

Fig. 2

CT attenuates the stemness of NSCLC CSCs. ad The IC50 values were measured in NSCLC cells and spheroids. eg The mRNA levels of nanog and Oct4 were detected in the NSCLC spheroids treated with different concentrations of CT as indicated. h, i The capacity of spheroid formation was determined in the spheroids described in (e) via measuring spheroid size (h) and number (i). j ALDH1 activity was examined in the spheroids depicted in (e). k, l The tumor-initiation ability was evaluated in NSCLC CSC with or without CT treatment, and CSC rate was calculated using ELDA software. Data were presented as the mean ± sd, **P < 0.01 vs. control (Solvent control)

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