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Table 2 19 potential activity compounds of Evodia rutaecarpa

From: Traditional Chinese medicine for anti-Alzheimer’s disease: berberine and evodiamine from Evodia rutaecarpa

Number Molecule name OB (%) BBB DL
1 Evodiamine 86.02 0.85 0.64
2 Goshuyuamide I 83.19 0.64 0.39
3 Evodiamide 73.77 0.81 0.28
4 N-(2-methylaminobenzoyl) tryptamine 56.96 0.8 0.26
5 Fordimine 55.11 0.75 0.26
6 Evocarpine 48.66 1.17 0.36
7 1-Methyl-2-[(Z)-undec-6-enyl]-4-quinolone 48.48 1.14 0.27
8 1-Methyl-2-[(Z)-pentadec-10-enyl]-4-quinolone 48.45 1.11 0.46
9 1-Methyl-2-nonyl-4-quinolone 48.42 1.21 0.2
10 1-Methyl-2-undecyl-4-quinolone 47.59 1.19 0.27
11 Icosa-11,14,17-trienoic acid methyl ester 44.81 1.07 0.23
12 1-Methyl-2-pentadecyl-4-quinolone 44.52 1.05 0.46
13 Dihydrorutaecarpine 42.27 0.7 0.6
14 Rutaecarpine 40.3 0.71 0.6
15 24-Methyl-31-norlanost-9(11)-enol 38 1 0.75
16 Beta-sitosterol 36.91 0.99 0.75
17 Sitosterol 36.91 0.87 0.75
18 Berberine 36.86 0.57 0.78
19 1-(5,7,8-Trimethoxy-2,2-dimethylchromen-6-yl) ethanone 30.39 0.75 0.18
  1. OB oral bioavailability, DL drug-likeness, BBB blood–brain barrier