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Fig. 3 | Chinese Medicine

Fig. 3

From: Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation

Fig. 3

The proliferation of SC induced by mSC could be effectively suppressed by JNK-inhibitor but p38-inhibitor nor ERK-inhibitor. a The effective blockage of the enhanced SC proliferation under mSC 200 μg/ml was only observed with JNK inhibitor (mSC + IH relative to JNK IH SP600125, 0.330 ± 0.057 and 0.463 ± 0.054 respectively, p = 0.0570, n = 3), b but not with p38 inhibitor (mSC + IH relative to p38 IH SB203580, 1.131 ± 0.051 and 0.389 ± 0.046 respectively, ****p < 0.0001, n = 3) nor c ERK inhibitor (mSC + IH relative to ERK IH U0126, 0.994 ± 0.044 and 0.500 ± 0.068, ****p < 0.0001, respectively, n = 3, one-way ANOVA with Tukey’s multiple comparisons)

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