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Fig. 4 | Chinese Medicine

Fig. 4

From: Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation

Fig. 4

Micronized sacchachitin (mSC) induced JNK/MAPK phosphorylation was predominantly initiated by the activation of TLR2 and mediated by TAK1. The protein level of TAK1 and JNK/MAPK were significantly suppressed by TLR2/4-inhibitor (TLR2/4 IH, 1.10 ± 0.05, p = 0.07, 0.55 ± 0.06, p = 0.13, n = 3, unpaired t-test) but not by TLR4-inhibitor (TLR4IH, 1.903 ± 0.016, 1.106 ± 0.052, *p < 0.05, n = 3, unpaired t-test)

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Chinese Medicine

ISSN: 1749-8546

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