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Fig. 5 | Chinese Medicine

Fig. 5

From: Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation

Fig. 5

AP-1 transcriptional activity was significantly enhanced by mSC. a The AP-1 transcriptional activity of the TA muscle isolated myogenic cells, included Pax7 + ve SCs, which were cultivated with mSC (200 μg/mL) contained medium was significantly enhanced relative to that of the control (1.713 ± 0.095, *p < 0.05, n = 3, unpaired t-test). b There was no remarkable increased in phosphorylation of NF-κB admitted (0.786 ± 0.045, p = 0.481, n = 3, unpaired t-test). c The enhancement of SC proliferation induced by mSC was predominantly through TLR2 and the activation of TAK 1-JNK-AP-1 signal pathway. Interestingly, JNK was solely activated among the MAPK signaling

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