Fig. 3

Effects of RAGE pre-treatment on protein expression in the tMCAO-induced mouse brain. a–c, representative image of western blot analysis of the expression of p-ERK, ERK, p-JNK, JNK, p-p38, p38, and β-actin in the ischemic ipsilateral cortex of the brain. d–f, representative image of western blot analysis of the expression of p-ERK, ERK, p-JNK, JNK, p-p38, p38, and β-actin in the ischemic ipsilateral hippocampus of the brain. All data are expressed as mean ± standard error (n = 3). ^#p < 0.05, ^###p < 0.001 vs. sham-operated group; * p < 0.05, *** p < 0.001 vs. tMCAO group