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Table 2 Pharmacokinetic parameters of decursin after oral administration of RAGE

From: Neuroprotective effect of Angelica gigas root in a mouse model of ischemic brain injury through MAPK signaling pathway regulation

Parameter Mean ± SD
AUC0-∞ (ng·hr/mL) 1218.319 ± 326.042
AUC0-t (ng·hr/mL) 1186.935 ± 323.500
Cmax (ng/mL) 407.888 ± 85.732
Tmax (hr) 1.750 ± 1.255
t1/2 (hr) 8.283 ± 0.538
MRT0-∞ (hr) 6.897 ± 0.954
MRT0-t (hr) 5.433 ± 0.581
Clast (ng/mL) 2.621 ± 0.665
  1. AUC0-t, the area under the curve from 0 time to 48 h; AUC0-∞, the area under the curve from 0 time to infinity; Cmax, the maximum drug concentration in plasma; t1/2, half-life; Tmax, time taken to reach maximum drug concentration in plasma; MRT0-∞ (hr), mean residence time from 0 to infinity last measured concentration; MRT0- t (hr), mean residence time from 0 time to 48 h; Clast, last measured concentration