Fig. 7

Trilobatin improved insulin resistance in ob/ob mice. Twenty male ob/ob mice were separated to two groups randomly, which were control (ob/ob) and trilobatin (ob/ob-Tri), ten same age of C57BL/6 male mice were used as negative control (C57BL6) in this study. After ob/ob mice were administrated with 10 mg/kg trilobatin (i. g.) for 4 weeks, the insulin content in serum (a), fasting blood glucose (b) and glucose tolerance test (d) was measured, HOMA-IR (c) and AUC (e) were calculated. Data are mean ± SD (n = 10). *p < 0.05, **p < 0.01 vs. C57BL6, ^#p < 0.05 vs. ob/ob