Fig. 9

Trilobatin affected the expression and distribution of GLUT4 in muscle tissue of ob/ob mice. After the ob/ob mice were administrated with 10 mg/kg trilobatin (i. g.) for 4 weeks, the expression (a), distribution of GLUT 4 in membranes (b) and cytoplasm (c) were detected by western blot or immunofluorescence (d). Data are mean ± SD of randomly selected three from ten mice, and the experiments were repeated at least three times. **p < 0.01 vs. C57BL6, ^##p < 0.01 vs. ob/ob