Skip to main content
Fig. 4 | Chinese Medicine

Fig. 4

From: Administration of a herbal formulation enhanced blastocyst implantation via IκB activation in mouse endometrium

Fig. 4

Effects of BCB on in vivo implantation rate in the RU486-induced implantation failure model. Female mice were administrated 300 mg/kg BCB for 18–21 days. On day 8, all females were mated with males, and days when vaginal plugs were first detected were designated as day 1 of pregnancy. The RU486 and RU486 plus BCB 300 groups were injected subcutaneously with RU486 solution (4 mg/kg, 0.08 mg/100 µL), while controls were injected with corn oil as vehicle on day 4 of pregnancy. Seven days after RU486 injection, mice were sacrificed, and uterine horns were excised. a Representative photographs of uterine horns showing embryo implantation sites. b Quantification of implanted embryos in each uterine horn. Data are presented as means ± SEMs. Groups are: the control group (n = 6), the RU486 group (RU486, n = 6) and the RU486 plus BCB 300 group (RU486 + BCB 300, n = 6). **p < 0.001 vs. controls

Back to article page