Table 5 The top 10 signaling pathways with related genes
Term | Pathway | Genes |
|---|---|---|
hsa04923 | Regulation of lipolysis in adipocytes | PIK3CG, AKT1, PTGS2, PIK3CB, PTGS1, PIK3CA, ADORA1, INSR, PIK3R1 |
hsa04917 | Prolactin signaling pathway | PIK3CG, AKT1, PIK3CB, MAPK14, GSK3B, ESR1, PIK3CA, STAT1, PIK3R1 |
hsa04668 | TNF signaling pathway | PIK3CG, AKT1, PTGS2, PIK3CB, MAPK14, MMP9, PIK3CA, MMP14, MMP3, PIK3R1 |
hsa04370 | VEGF signaling pathway | PIK3CG, AKT1, PTGS2, PIK3CB, MAPK14, PIK3CA, PIK3R1, KDR |
hsa04068 | FoxO signaling pathway | PIK3CG, AKT1, EGFR, IGF1R, PIK3CB, MAPK14, PIK3CA, INSR, PIK3R1, CDK2 |
hsa04915 | Estrogen signaling pathway | PIK3CG, AKT1, EGFR, PIK3CB, MMP9, ESR1, PIK3CA, MMP2, PIK3R1 |
hsa00591 | Linoleic acid metabolism | CYP3A4, ALOX15, CYP2C19, CYP2C9, PLA2G1B, CYP1A2 |
hsa04015 | Rap1 signaling pathway | PIK3CG, AKT1, EGFR, IGF1R, ADORA2A, PIK3CB, MAPK14, PIK3CA, INSR, PIK3R1, KDR |
hsa00590 | Arachidonic acid metabolism | ALOX15, CYP2C19, PTGS2, CYP2C9, PTGS1, PLA2G1B, ALOX12 |
hsa04380 | Osteoclast differentiation | PIK3CG, AKT1, PIK3CB, MAPK14, LCK, PIK3CA, STAT1, PIK3R1, SYK |