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Table 2 Effects of HG/[6]-GR on hemodynamic indices in rats

From: Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

Group LVSP (mmHg) LVEDP (mmHg)  + dp/dtmax (mmHg/s) -dp/dtmax (mmHg/s)
C 140.56 ± 12.75 − 12.97 ± 2.85 7506.87 ± 668.49 − 5330.51 ± 884.92
DOX 51.57 ± 8.38** 10.54 ± 1.83** 2313.95 ± 416.24** − 1386.08 ± 172.61**
DH 132.04 ± 10.48## − 7.40 ± 0.89## 8579.56 ± 873.29## − 6757.02 ± 601.40##
HG 112.30 ± 10.91## − 1.47 ± 2.59## 9034.06 ± 426.66## − 6778.09 ± 291.51##
[6]-GR 100.91 ± 12.02## 7.34 ± 0.86## 5029.14 ± 256.68## − 3729.03 ± 104.06##
HG/[6]-GR 125.25 ± 7.92##abb − 4.07 ± 0.93##abb 10,263.24 ± 1056.67##aabb − 8428.85 ± 399.13##aabb
  1. Compared with the control group
  2. **P < 0.01; compared with the DOX group
  3. ##P < 0.01; compared with the HG group
  4. aP < 0.05
  5. aaP < 0.01; compared with the [6]-GR group
  6. bbP < 0.01
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Chinese Medicine

ISSN: 1749-8546

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