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Table 2 Effects of HG/[6]-GR on hemodynamic indices in rats

From: Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

Group

LVSP (mmHg)

LVEDP (mmHg)

 + dp/dtmax (mmHg/s)

-dp/dtmax (mmHg/s)

C

140.56 ± 12.75

− 12.97 ± 2.85

7506.87 ± 668.49

− 5330.51 ± 884.92

DOX

51.57 ± 8.38**

10.54 ± 1.83**

2313.95 ± 416.24**

− 1386.08 ± 172.61**

DH

132.04 ± 10.48##

− 7.40 ± 0.89##

8579.56 ± 873.29##

− 6757.02 ± 601.40##

HG

112.30 ± 10.91##

− 1.47 ± 2.59##

9034.06 ± 426.66##

− 6778.09 ± 291.51##

[6]-GR

100.91 ± 12.02##

7.34 ± 0.86##

5029.14 ± 256.68##

− 3729.03 ± 104.06##

HG/[6]-GR

125.25 ± 7.92##abb

− 4.07 ± 0.93##abb

10,263.24 ± 1056.67##aabb

− 8428.85 ± 399.13##aabb

  1. Compared with the control group
  2. **P < 0.01; compared with the DOX group
  3. ##P < 0.01; compared with the HG group
  4. aP < 0.05
  5. aaP < 0.01; compared with the [6]-GR group
  6. bbP < 0.01