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Table 3 Identified metabolites of the serum sample from different groups

From: Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

No Compound Name Formula Mass (m/z) Retention time (min) Ratio changes (significance)
Control/DOX HG/[6]-GR /DOX
1 Acetylphosphate C2H5O5P 139.9872 20.01 4.57** 3.98##
2 3-Carboxy-1-hydroxypropylthiamine diphosphate C16H25N4O10P2S 527.0692 13.79 1.46** 1.48##
3 Coenzyme A C21H36N7O16P3S 767.1152 11.45 3.95** 3.54##
4 Palmitic acid C16H32O2 256.2402 16.37 0.39** 0.54##
5 PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z)) C37H66NO8P 683.4375 20.46 3.57** 3.05##
6 Oleic acid C18H34O2 287.2819 7.84 3.30** 3.10##
7 LysoPC(18:1(9Z)) C24H51NO6P 480.3086 15.87 1.85** 1.75##
8 PC(16:0/16:0) C46H83NO8P 808.5856 15.33 0.43** 0.64##
  1. Compared with the control group
  2. **P < 0.01; compared with the DOX group
  3. ##P < 0.01
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Chinese Medicine

ISSN: 1749-8546

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