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Table 3 Identified metabolites of the serum sample from different groups

From: Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats

No

Compound Name

Formula

Mass (m/z)

Retention time (min)

Ratio changes (significance)

Control/DOX

HG/[6]-GR /DOX

1

Acetylphosphate

C2H5O5P

139.9872

20.01

4.57**

3.98##

2

3-Carboxy-1-hydroxypropylthiamine diphosphate

C16H25N4O10P2S

527.0692

13.79

1.46**

1.48##

3

Coenzyme A

C21H36N7O16P3S

767.1152

11.45

3.95**

3.54##

4

Palmitic acid

C16H32O2

256.2402

16.37

0.39**

0.54##

5

PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))

C37H66NO8P

683.4375

20.46

3.57**

3.05##

6

Oleic acid

C18H34O2

287.2819

7.84

3.30**

3.10##

7

LysoPC(18:1(9Z))

C24H51NO6P

480.3086

15.87

1.85**

1.75##

8

PC(16:0/16:0)

C46H83NO8P

808.5856

15.33

0.43**

0.64##

  1. Compared with the control group
  2. **P < 0.01; compared with the DOX group
  3. ##P < 0.01