Fig. 2

Metformin or Catechins treatment reduces uterine weight, hormone secretion and insulin resistance in mice. a Body weight was measured in different groups in mice after 28 days treatment. b Uterus weight was measured in different groups in mice after 28 days treatment. c Uterus/body weight was calculated in different groups in mice after 28 days treatment. d The estrogen content in serum was measured in different groups in mice after 28 days treatment. e The follicle stimulating hormone content in serum was measured in different groups in mice after 28 days treatment. f The luteinizing hormone content in serum was measured in different groups in mice after 28 days treatment. g The fasting blood glucose level was measured in different groups in mice after 28 days treatment. h The fasting insulin level in serum was measured in different groups in mice after 28 days treatment. i HOMA-IR (Homeostatic model assessment of insulin resistance) was calculated in different groups in mice. HOMA-IR = fasting blood glucose × fasting serum insulin/22.5. N = 10 in each group. A P value of < 0.05 was considered statistically significant