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Fig. 8 | Chinese Medicine

Fig. 8

From: Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice

Fig. 8

Catechins inhibits STAT3 signaling in uterus of mice. a The immunohistochemical staining of p-STAT3 was performed in uterus in control or model mice with or without 100 mg/kg catechins treatment for 28 days. Different magnifications of representative images were displayed. Scale bar in low magnification = 500 μm. The boxed area in black color were shown by a higher magnification. Scale bar in high magnification = 50 μm. b Related to 8A, the mean optical density analysis of p-STAT3 in uterus was performed in different groups in mice. N = 6 in each group. c Representative images of western blot analysis of STAT3, p-STAT3, IRS1, p-IRS1, PI3K and p-PI3K were displayed in uterus in control or model mice with or without 100 mg/kg catechins treatment for 28 days. d Related to 8C, the relative quantitative analysis was performed of p- STAT3/STAT3of western blot analysis in uterus in different groups in mice. N = 4 in each group. e Related to 8C, the relative quantitative analysis was performed of p- IRS1/IRS1of western blot analysis in uterus in different groups in mice. N = 4 in each group. f Related to 8C, the relative quantitative analysis was performed of p-PI3K/PI3Kof western blot analysis in uterus in different groups in mice. N = 4 in each group. A P value of < 0.05 was considered statistically significant

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