Table 4 Detailed information of perturbed glycerophospholipids among different comparison group
Metabolites | m/z | Retention time (min) | Detection mode | (NC vs. OPD) | (NC vs. OPD') | (OPD vs. OPD') | |||
|---|---|---|---|---|---|---|---|---|---|
VIP | FC | VIP | FC | VIP | FC | ||||
LPC(16:1) | 538.3150 | 2.1049 | Negative | 1.80 | 0.54 | 1.69 | 0.68 | / | / |
MePC(19:4e) | 566.3217 | 2.3768 | Positive | 1.94 | 1.50 | / | / | 1.51 | 0.82 |
MePC(38:8e) | 824.5565 | 9.3435 | Positive | 1.32 | 1.72 | 1.23 | 1.45 | / | / |
PC(16:1_18:2) | 800.5447 | 6.9216 | Negative | 1.46 | 0.57 | / | / | / | / |
PC(18:1_22:6) | 876.5760 | 7.5938 | Negative | 1.42 | 0.58 | 1.38 | 0.67 | / | / |
PC(16:0_16:1) | 776.5447 | 8.1717 | Negative | 1.05 | 0.63 | / | / | 1.54 | 1.76 |
PC(40:6) | 834.6007 | 8.3262 | Positive | 1.13 | 0.71 | / | / | / | / |
PC(18:1_20:4) | 852.5760 | 8.1460 | Negative | 2.86 | 0.75 | / | / | 2.60 | 1.31 |
PC(36:2) | 786.6007 | 9.3590 | Positive | 8.17 | 1.24 | 6.62 | 1.12 | / | / |
PC(18:1e_16:0) | 790.5967 | 9.6227 | Negative | 1.08 | 1.27 | / | / | / | / |
PC(18:1_18:1) | 808.5827 | 9.3608 | Positive | 2.70 | 1.35 | / | / | / | / |
PC(18:0_20:5) | 808.5851 | 9.3512 | Positive | 2.70 | 1.35 | / | / | / | / |
PC(34:1e) | 746.6058 | 9.5947 | Positive | 1.07 | 1.39 | 1.11 | 1.28 | / | / |
PC(34:2e) | 744.5902 | 9.0343 | Positive | 1.03 | 2.37 | / | / | 1.07 | 0.47 |
PI(19:0e) | 613.3358 | 2.2930 | Negative | 1.02 | 0.79 | 1.54 | 0.73 | / | / |
PS(37:2) | 800.5447 | 6.9216 | Negative | 1.46 | 0.57 | / | / | / | / |
SPH(d20:0) | 330.3367 | 2.9837 | Positive | 1.50 | 1.56 | / | / | / | / |
SPH(t16:0) | 290.2690 | 1.2942 | Positive | 1.52 | 3.07 | 1.23 | 2.16 | / | / |
cPA(18:2) | 415.2255 | 2.5302 | Negative | / | / | 1.08 | 0.40 | / | / |
cPA(16:0) | 391.2255 | 2.9310 | Negative | / | / | 1.41 | 0.53 | / | / |
cPA(18:0) | 419.2568 | 3.4579 | Negative | / | / | 1.16 | 0.57 | / | / |
dMePE(40:7) | 816.5549 | 7.8982 | Negative | / | / | 2.49 | 1.83 | / | / |
LPC(17:0) | 554.3463 | 3.0918 | Negative | / | / | 1.57 | 0.69 | / | / |
LPC(18:2) | 564.3307 | 2.4355 | Negative | / | / | 6.31 | 0.85 | / | / |
PC(20:4_20:4) | 874.5604 | 6.4729 | Negative | / | / | 1.26 | 0.77 | / | / |
PC(18:0_18:2) | 830.5917 | 9.3742 | Negative | / | / | 6.21 | 1.12 | / | / |
PC(16:0_18:1) | 804.5760 | 9.2239 | Negative | / | / | 4.46 | 1.15 | 5.42 | 1.28 |
PC(34:0) | 762.6007 | 9.8127 | Positive | / | / | 1.22 | 1.16 | / | / |
PC(18:1e_20:4) | 838.5967 | 8.9016 | Negative | / | / | 1.26 | 1.25 | / | / |
PC(18:1e_16:0) | 790.5967 | 9.6227 | Negative | / | / | 1.32 | 1.26 | / | / |
PC(16:1e_20:4) | 810.5654 | 8.6947 | Negative | / | / | 1.13 | 1.79 | / | / |
LPC(18:0) | 568.3620 | 3.3742 | Negative | / | / | / | / | 3.49 | 0.84 |
PC(34:1) | 760.5851 | 9.2172 | Positive | / | / | / | / | 4.81 | 1.19 |
PC(16:0_16:0) | 778.5604 | 9.2035 | Negative | / | / | / | / | 2.45 | 1.29 |
PC(14:0_18:2) | 774.5291 | 6.7773 | Negative | / | / | / | / | 1.07 | 2.03 |