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Table 4 Detailed information of perturbed glycerophospholipids among different comparison group

From: Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo

Metabolites m/z Retention time (min) Detection mode (NC vs. OPD) (NC vs. OPD') (OPD vs. OPD')
VIP FC VIP FC VIP FC
LPC(16:1) 538.3150 2.1049 Negative 1.80 0.54 1.69 0.68 / /
MePC(19:4e) 566.3217 2.3768 Positive 1.94 1.50 / / 1.51 0.82
MePC(38:8e) 824.5565 9.3435 Positive 1.32 1.72 1.23 1.45 / /
PC(16:1_18:2) 800.5447 6.9216 Negative 1.46 0.57 / / / /
PC(18:1_22:6) 876.5760 7.5938 Negative 1.42 0.58 1.38 0.67 / /
PC(16:0_16:1) 776.5447 8.1717 Negative 1.05 0.63 / / 1.54 1.76
PC(40:6) 834.6007 8.3262 Positive 1.13 0.71 / / / /
PC(18:1_20:4) 852.5760 8.1460 Negative 2.86 0.75 / / 2.60 1.31
PC(36:2) 786.6007 9.3590 Positive 8.17 1.24 6.62 1.12 / /
PC(18:1e_16:0) 790.5967 9.6227 Negative 1.08 1.27 / / / /
PC(18:1_18:1) 808.5827 9.3608 Positive 2.70 1.35 / / / /
PC(18:0_20:5) 808.5851 9.3512 Positive 2.70 1.35 / / / /
PC(34:1e) 746.6058 9.5947 Positive 1.07 1.39 1.11 1.28 / /
PC(34:2e) 744.5902 9.0343 Positive 1.03 2.37 / / 1.07 0.47
PI(19:0e) 613.3358 2.2930 Negative 1.02 0.79 1.54 0.73 / /
PS(37:2) 800.5447 6.9216 Negative 1.46 0.57 / / / /
SPH(d20:0) 330.3367 2.9837 Positive 1.50 1.56 / / / /
SPH(t16:0) 290.2690 1.2942 Positive 1.52 3.07 1.23 2.16 / /
cPA(18:2) 415.2255 2.5302 Negative / / 1.08 0.40 / /
cPA(16:0) 391.2255 2.9310 Negative / / 1.41 0.53 / /
cPA(18:0) 419.2568 3.4579 Negative / / 1.16 0.57 / /
dMePE(40:7) 816.5549 7.8982 Negative / / 2.49 1.83 / /
LPC(17:0) 554.3463 3.0918 Negative / / 1.57 0.69 / /
LPC(18:2) 564.3307 2.4355 Negative / / 6.31 0.85 / /
PC(20:4_20:4) 874.5604 6.4729 Negative / / 1.26 0.77 / /
PC(18:0_18:2) 830.5917 9.3742 Negative / / 6.21 1.12 / /
PC(16:0_18:1) 804.5760 9.2239 Negative / / 4.46 1.15 5.42 1.28
PC(34:0) 762.6007 9.8127 Positive / / 1.22 1.16 / /
PC(18:1e_20:4) 838.5967 8.9016 Negative / / 1.26 1.25 / /
PC(18:1e_16:0) 790.5967 9.6227 Negative / / 1.32 1.26 / /
PC(16:1e_20:4) 810.5654 8.6947 Negative / / 1.13 1.79 / /
LPC(18:0) 568.3620 3.3742 Negative / / / / 3.49 0.84
PC(34:1) 760.5851 9.2172 Positive / / / / 4.81 1.19
PC(16:0_16:0) 778.5604 9.2035 Negative / / / / 2.45 1.29
PC(14:0_18:2) 774.5291 6.7773 Negative / / / / 1.07 2.03