Fig. 4
From: Beneficial effect of Indigo Naturalis on acute lung injury induced by influenza A virus
Effect of INAE on lung injury, lung index, body weight and virus titer of IAV-infected mice. Mice were infected with 3 × LD50 of IAV and administered orally with INAE, ribavirin or 0.5% CMC-Na at indicated doses once daily for 4 days. Lung index, mice body weight, and virus titer were calculated and detected. Lung photos and hematoxylin–eosin stain (H&E) with vision of ×200  (a). Lung index = Lung weight / body weight × 100% (b). Mice body weight growth curve (c). Virus titer in lung homogenate of mice (d). Data were presented as mean ± S.D. (n = 6). **P < 0.01, ***P < 0.001 compared with model group, tested by ANOVA and Fisher’s PLSD