Fig. 2

Gene ontology (GO) function enrichment analyses of the Zheng-specific genes and the targets of the Zheng-specific miRNAs discovered in the different case populations. a Bubble diagrams showing the enriched GO function terms of PDHS-specific genes (left) and PQDS-specific genes (right) in leukocytes. b Heatmaps indicating the GO function enrichment results of the validated targets of PDHS-specific miRNAs (left) and PQDS-specific miRNAs (right) in leukocytes. The common GO terms between the two Zhengs were shown in bold font. c Heatmaps displaying the enriched GO function terms of the validated targets of PDHS-specific miRNAs (left) and PQDS-specific miRNAs (right) in serums. The common GO terms between the two Zhengs were shown in bold font. The pink highlighted GO terms indicate the commonly enriched GO terms of the validated targets of the PDHS-miRNAs in the leukocytes and corresponding serums. The indigo highlighted GO terms mark the commonly enriched GO terms of the validated targets of the PQDS-miRNAs in the leukocytes and corresponding serums. PQDS chronic atrophic gastritis patients with Pi-qi-deficiency syndrome, PDHS chronic atrophic gastritis patients with Pi-wei damp-heat syndrome