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Table 1 Models of depression

From: The mechanism of electroacupuncture for depression on basic research: a systematic review

Animal Model type Modeling time Microbiology level Sex Strain References
Rat WKY - SPF Male Wistar [20,21,22]
CUMS 56 days
28 days
SPF
SPF
Male
Male
Sprague–Dawley
Wistar
Wistar
[23]
[24]
[25]
CUS 70 days
49 days
28 days
SPF
SPF
SPF
Male
Male
Male
Sprague–Dawley
Sprague–Dawley
Sprague–Dawley
[26]
[27]
[28]
CUMS 21 days SPF
CL
Male
Male
Sprague–Dawley
Wistar
Sprague–Dawley
[29,30,31,32,33]
[34,35,36,37]
[38]
CUMS 14 days SPF Male Sprague–Dawley [39]
CRS 21 days
28 days
SPF
SPF
Male
Male
Sprague–Dawley
Sprague–Dawley
[40]
[41]
CMS 28 days
77 days
SPF
SPF
Male
Male
Sprague–Dawley
Sprague–Dawley
[42]
[43]
Pain-depression dyad 3 days SPF Male Sprague–Dawley [44]
PSD 3 days SPF Male Sprague–Dawley [45]
6-OHDA-lesioned - SPF Male Sprague–Dawley [46]
MS 21 days SPF Male Wistar [47]
  1. WKY Wistar Kyoto, CUMS chronic unpredictable mild stress, CRS chronic restraint stress, 6-OHDA 6-hydroxydopamine, PSD poststroke depression, MS maternal separation, SPF specified pathogen free, CL clean animal