Fig. 7

HXWTF improved angiogenic function and blocked CaMKII oxidation and phosphorylation of HCMECs treated with H/SD. Tube formation on Matrigel was examined in HCMECs (a). Immunofluorescence staining of HCMECs were positive for CD34 (b). Scaling is as indicated, Scale bar 100 μm. Western blot analysis of CD34, p-CaMKII, ox-CaMKII and total CaMKII expressions in H/SD-treated HCMECs (c–g). HCMECs, Human cardiac microvascular endothelial cells. **P< 0.01, *P< 0.05 compared to the sham group; ^##P< 0.01, ^#P< 0.05 compared to the model group. Values are presented as mean ± SD (n = 4 per group)