Fig. 6From: Wrist–ankle acupuncture attenuates cancer-induced bone pain by regulating descending pain-modulating system in a rat modelEffects of WAA on 5-HT3AR and MOR immunohistochemical expression. Values are mean ± standard deviations (n = 4) of positive proportion. *P < 0.05 vs. CIBP group; #P < 0.05 vs. model groups (CIBP, EA, and WAA groups). CIBP cancer-induced bone pain, EA electroacupuncture, WAA wrist–ankle acupuncture, 5-HT3AR 5-hydroxytryotamine type 3A receptor, MOR μ-opioid receptor, SDH superficial layers of the dorsal horn, RVM rostral ventromedial medullaBack to article page