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Fig. 7 | Chinese Medicine

Fig. 7

From: Wrist–ankle acupuncture attenuates cancer-induced bone pain by regulating descending pain-modulating system in a rat model

Fig. 7

Effects of WAA on 5-HT, β-EP, EM-1, and EM-2 levels. a1 Effects of WAA on 5-HT level in spinal cord; a2 Effects of WAA on 5-HT level in RVM; b1 Effects of WAA on β-EP level in spinal cord; b2 Effects of WAA on β-EP level in RVM; c1 Effects of WAA on EM-1 level in spinal cord; c2 Effects of WAA on EM-1 level in RVM; d1 Effects of WAA on EM-2 level in spinal cord; d2 Effects of WAA on EM-2 level in RVM. Values are mean ± standard deviations (n = 4) of positive proportion. *P < 0.05 vs. CIBP group; #P < 0.05 vs. model groups (CIBP, EA, and WAA groups). CIBP cancer-induced bone pain, EA electroacupuncture, WAA wrist–ankle acupuncture, 5-HT 5-hydroxytryotamine, β-EP β-endorphin, EM-1 endomorphin-1, EM-2 endomorphin-2, RVM rostral ventromedial medulla

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