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Fig. 4 | Chinese Medicine

Fig. 4

From: A metabolic exploration of the protective effect of Ligusticum wallichii on IL-1β-injured mouse chondrocytes

Fig. 4

Differential metabolome related to IL-1β and L. wallichii treatment. a Heat map for relative abundances of differential metabolites (n = 59) in IL-1β-treated primary mouse chondrocytes compared with the untreated cells. b Heat map for relative abundances of differential metabolites (n = 47) in IL-1β + L. wallichii-treated primary mouse chondrocytes compared with IL-1β-treated primary mouse chondrocytes. Blue and yellow present decrease and increase of metabolites relative to the median metabolite level, respectively (see color scale). c Venn diagram exhibiting the overlap of differential metabolites between the IL-1β and IL-1β + L. wallichii groups. Up-regulated and down-regulated metabolites are indicated with red and green arrows, respectively. d The number of metabolites increased and decreased in different metabolic categories

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