Fig. 6

Pathway enrichment analysis and potential metabolic mechanisms of IL-1β-induced injury in chondrocytes and protection by L. wallichii. a By using an online tool, Metaboanalyst 4.0 (http://www.metaboanalyst.ca/), several pathways were enriched. The corresponding metabolites were shown in every metabolic pathway. b The metabolic flow of primary mouse chondrocytes treated by IL-1β or IL-1β + L. wallichii. Symbol circle and square represent the relative metabolite changes in the IL-1β group and the IL-1β + L. wallichii groups, respectively. The decrease, increase and no change in levels with statistical significance are presented in green, red and yellow, respectively