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Table 4 Main KEGG pathways significantly relating to major hubs

From: Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma

Term Pathway Count Pop Hits P Value
hsa05200 Pathways in cancer 41 393 6.63E−27
hsa05161 Hepatitis B 27 145 1.73E−23
hsa05205 Proteoglycans in cancer 23 200 3.70E−15
hsa04151 PI3K-Akt signaling pathway 23 345 2.43E−10
hsa05166 HTLV-I infection 19 254 2.58E−09
hsa05206 MicroRNAs in cancer 19 286 1.70E−08
hsa05152 Tuberculosis 18 177 6.66E−11
hsa04510 Focal adhesion 18 206 7.34E−10
hsa05219 Bladder cancer 17 41 1.18E−20
hsa04066 HIF-1 signaling pathway 17 96 4.41E−14
hsa05160 Hepatitis C 17 133 8.19E−12
hsa04010 MAPK signaling pathway 17 253 1.11E−07
hsa05210 Colorectal cancer 16 62 7.74E−16
hsa05212 Pancreatic cancer 16 65 1.78E−15
hsa05215 Prostate cancer 16 88 2.09E−13
hsa05142 Chagas disease (American trypanosomiasis) 16 104 2.67E−12
hsa05145 Toxoplasmosis 16 110 6.18E−12
hsa05164 Influenza A 16 174 4.54E−09
hsa05223 Non-small cell lung cancer 15 56 4.75E−15
hsa04012 ErbB signaling pathway 15 87 3.24E−12