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Fig. 4 | Chinese Medicine

Fig. 4

From: Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism

Fig. 4

Thermogenesis-promoting effect of AA was associated with BAs. (a−c) The levels of total bile acids (BAs) (a), total primary bile acids (PBAs) (b), and total secondary bile acids (SBAs) (c) in serum.  Specific levels of PBAs (d) and SBAs (e) in serum. Control, CH, and CH+ AA represent groups intermittently exposed to warm water (32 ± 0.5 °C), cold water (3.5 ± 0.5 °C), and cold water plus AA, respectively. CA, cholic acid; CDCA, chenodeoxycholic acid; α-MCA, α-muricholic acid; β-MCA, β-muricholic acid; T-αMCA, tauro-α-muricholic acid; TCDCA, taurochenodeoxycholic acid; GCDCA, glycoursodeoxycholic acid; GCA, glycocholic acid; DCA, deoxycholic acid; LCA, lithocholic acid; UDCA, ursodeoxycholic acid; ω-MCA, ω-murichoclic acid; GDCA, glycodeoxycholic acid; TLCA, taurolithocholic acid; THDCA, taurohyodeoxycholic acid; TUDCA, tauroursodeoxycholic acid. Data were expressed as mean ± standard deviation (SD) (n = 6 rats/group). Differences were evaluated by one-way ANOVA with a post hoc Student–Newman–Keuls test (*P < 0.05 and **P < 0.01 )

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