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Table 2 MIC and MBC of S. officinalis against multiple H. pylori strains

From: In vitro anti‐bacterial activity and network pharmacology analysis of Sanguisorba officinalis L. against Helicobacter pylori infection

No. Strains Drug sensitivity a MIC b
(µg/ml)
MIC c(µg/ml) MBC (µg/ml) MBC/MIC
1 ATCC43504 R(MTZ) 160 160 640 4
2 ATCC700392 S 160 160 640 4
3 SS1 S 160 160 640 4
4 CSO1 R(CLR) 320 320 640 2
5 LQ2# R(CLR, AMO, LEF) 320 320 640 2
6 ICDC11101 R(MET, LEF) 160 80 640 2
7 QYZ-001 R(MTZ) 320 / 640 2
8 QYZ-003 R(CLR, MTZ, LEF) 160 / 320 2
9 QYZ-004 R(CLR, MTZ, LEF, AMO) 160 / 320 2
  1. aS drug sensitive, R drug resistant, CLR clarithromycin, MTZ  metronidazole, LEF levofloxacin, AMO amoxicin. The breakpoint values of drug resistance were determined according to EUCAST 2019 (European Committee on Antimicrobial Susceptibility Testing).  bresults of using micro-broth dilution method; cresults of agar dilution method
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