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Table 2 MIC and MBC of S. officinalis against multiple H. pylori strains

From: In vitro anti‐bacterial activity and network pharmacology analysis of Sanguisorba officinalis L. against Helicobacter pylori infection

No.

Strains

Drug sensitivity a

MIC b

(µg/ml)

MIC c(µg/ml)

MBC (µg/ml)

MBC/MIC

1

ATCC43504

R(MTZ)

160

160

640

4

2

ATCC700392

S

160

160

640

4

3

SS1

S

160

160

640

4

4

CSO1

R(CLR)

320

320

640

2

5

LQ2#

R(CLR, AMO, LEF)

320

320

640

2

6

ICDC11101

R(MET, LEF)

160

80

640

2

7

QYZ-001

R(MTZ)

320

/

640

2

8

QYZ-003

R(CLR, MTZ, LEF)

160

/

320

2

9

QYZ-004

R(CLR, MTZ, LEF, AMO)

160

/

320

2

  1. aS drug sensitive, R drug resistant, CLR clarithromycin, MTZ  metronidazole, LEF levofloxacin, AMO amoxicin. The breakpoint values of drug resistance were determined according to EUCAST 2019 (European Committee on Antimicrobial Susceptibility Testing).  bresults of using micro-broth dilution method; cresults of agar dilution method