Fig. 3

In vivo colon targeting and retention of shellac-coated zein MPs in colitis mice, mediated by the indication of IR780 encapsulation. a In vivo fluorescence imaging of the entire colitis mice with oral administration of free IR780, IR780/zein MPs and shellac@IR780/zein MPs at the post-administration 3 h, 6 h, 12 h and 24 h, respectively; b At 24 h post-administration, colon tissues in each group were dissected and observed by ex vivo fluorescence imaging