Table 1 Chromatographic and mass data of the 28 compounds of CG analyzed by HPLC-QQQ-MS/MS

1

Gallic acid

C₇H₆O₅

[M−H]⁻

125.02, 107.02, 81.03

D

2

Chlorogenic acid

C₁₆H₁₈O₉

[M−H]⁻

191.05, 179.03, 135.04

A, D, E, F, G

3

Isochlorogenic acid

C₁₆H₁₈O₉

[M−H]⁻

–

E, F, G

4

Caffeic acid

C₉H₈O₄

[M−H]⁻

135.04

B, E, G,

5

Albiflorin

C₂₃H₂₈O₁₁

[M+COOH]⁻, [M+Na]⁺

525.16, 479.16, 327.11, 381.04, 341.15

D

6

Paeoniflorin

C23H28O11

[M+COOH]⁻, [M+Na]⁺

525.15, 479.16, 327.11 -

D

7

Ethyl gallate

C₉H₁₀O₅

[M−H]⁻

169.12

D

8

Ferulic acid

C₁₀H₁₀O₄

[M−H]⁻

149.06, 134.03

A, B

9

Tetrahydropalmatine

C₂₁H₂₅NO₄

[M+H]⁺

341.16, 192.09, 165.08

I

10

Isocorynoxeine

C₂₂H₂₆NO₄

[M+H]⁺

351.17, 319.14,187.13

E

11

Rosmarinic acid

C₁₈H₁₆O₈

[M−H]⁻

197.04, 135.04, 161.02

G

12

Corydaline

C₂₂H₂₇NO₄

[M+H]⁺

355.18, 340.16

I

13

Rubrofusarin-gentiobioside

C₂₇H₃₂O₁₅

[M−H]⁻

273.08, 271.06, 256.04

H

14

Palmatine

C₂₁H₂₂NO₄

M⁺

336.13, 321.10, 294.11,

I

15

Berberine

C₂₀H₁₇NO₄

M⁺

321.10, 320.09, 304.10

I

16

Dehydrocorydaline

C₂₂H₂₄NO₄

M⁺

351.15, 336.15, 321.10

I

17

Cassiaside C

C₂₇H₃₂O₁₅

[M+COOH]⁻

641.21

H

18

Physcion-glucoside

C₂₂H₂₂O₁₀

[M−H]⁻

283.06, 268.06, 212.04

H

19

aurantio-obtusin

C₁₇H₁₄O₇

[M−H]⁻

314.04, 285.04, 299.02,

H

20

Rhein

C₁₅H₈O₆

[M−H]⁻

239.03, 211.02

H

21

Physcion

C₁₆H₁₂O₅

[M−H]⁻

268.03, 240.04, 239.04

H

22

chryso-obtusin

C₁₉H₁₈O₇

[M−H]⁻

342.07, 312.03, 284.03

H

23

Senkyunolide A

C₁₂H₁₆O₂

[M+H]⁺

173.10, 145.10, 135.05

A, B

24

Butylphthalide

C₁₂H₁₄O₂

[M+H]⁺

173.10, 145.10, 135.05

A, B

25

Obtusifolin

C₁₆H₁₂O₅

[M−H]⁻

268.03, 240.04

H

26

Z-Ligustilide

C₁₂H₁₄O₂

[M+H]⁺

173.10, 145.10, 135.04

A, B

27

Emodin

C₁₅H₁₀O₅

[M−H]⁻

241.05, 225.05

H

28

E-Ligustilide

C₁₂H₁₄O₂

[M+H]⁺

173.10, 145.10, 135.04

A, B