Table 2 Metabolites detected by LC-Q-TOF–MS in the validation sample set (HTN-PDS patients with body mass index from normal to high (N–H))/high to normal (H-N)) and their biological variation
Rt | Mass | Name | Formula | Folder | RV |
|---|---|---|---|---|---|
Hypertensive patients with BMI from normal to high (N–H) | |||||
883.853 | 923.7343 | PC(22:2(13Z,16Z)/24:1(15Z)) | C54H102NO8P | − 4.2589 | 0.30 |
488.784 | 493.3168 | LysoPC(16:1(9Z)) | C24H48NO7P | − 1.3129 | 0.20 |
502.977 | 520.2719 | Dolichyl diphosphate | C25H46O7P2 | 1.1990 | 0.10 |
515.839 | 761.4996 | PE(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) | C43H72NO8P | 1.7277 | 0.10 |
275.788 | 491.0008 | dATP | C10H16N5O12P3 | − 1.3376 | 0.08 |
863.462 | 858.5258 | PI(16:0/20:4(5Z,8Z,11Z,14Z)) | C45H79O13P | 5.7789 | 0.06 |
868.575 | 858.5692 | All-trans-Decaprenyl diphosphate | C50H84O7P2 | 5.7789 | 0.02 |
256.068 | 432.066 | Se-Adenosylselenohomocysteine | C14H20N6O5Se | 1.0574 | 0.02 |
1170.565 | 412.0185 | dIDP | C10H14N4O10P2 | − 2.4528 | 0.01 |
277.447 | 482.9845 | Cytidine triphosphate (CTP) | C9H16N3O14P3 | 1.2429 | 0.01 |
Hypertensive patients with BMI from high to normal (H-N) | |||||
1141.523 | 705.5309 | PC(14:0/16:0) | C38H76NO8P | 6.4684 | 0.32 |
652.833 | 420.3603 | 3b,5a,6b-Cholestanetriol | C27H48O3 | − 7.4571 | 0.16 |
521.412 | 722.444 | Octaprenyl diphosphate | C40H68O7P2 | 2.4689 | 0.12 |
190.274 | 141.0426 | 2-aminomuconic acid semialdehyde | C6H7NO3 | − 4.6339 | 0.10 |
61.626 | 129.0426 | Pyroglutamic acid | C5H7NO3 | 6.5815 | 0.08 |
223.019 | 189.0637 | N-Acetyl-L-glutamic acid | C7H11NO5 | 3.2199 | 0.06 |
324.918 | 462.2618 | Retinyl beta-glucuronide | C26H38O7 | 4.5571 | 0.05 |
89.597 | 168.0283 | Uric acid | C5H4N4O3 | − 1.7995 | 0.03 |
864.632 | 130.063 | 3-Methyl-2-oxovaleric acid | C6H10O3 | 3.3563 | 0.02 |
190.188 | 175.0633 | 3-Indoleacetic Acid | C10H9NO2 | − 1.0880 | 0.02 |
66.389 | 190.0114 | Oxalosuccinic acid | C6H6O7 | − 3.0817 | 0.02 |
51.332 | 339.0468 | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate | C9H14N3O9P | − 13.5318 | 0.01 |
63.879 | 112.016 | 2-Furoic acid | C5H4O3 | − 2.4225 | 0.01 |
625.18 | 362.2093 | 18-Hydroxycorticosterone | C21H30O5 | 3.9819 | 0.01 |