Fig. 1From: Herbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecologyThe relationships between gut microbiota and NAFLD. Enterotoxin (endotoxin, lipopolysaccharide) can damage intestinal epithelial cells and destroy their barrier function, enhancing the systemic absorption of toxins. Intestinal toxins pass from the intestinal lumen to the liver through the mesenteric circulation and lymphatic system, leading to inflammation. High fat diet rich in saturated and fatty acids can induce changes in bile acid composition of the body, thus abnormal bile acid metabolism in which bacteria live and leading to intestinal flora imbalanceBack to article page