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Table 1 Chemical component, isolated and identified methods and pharmacology activity on Filifoliumsibiricum (L.)Kitam

From: A comprehensive review of the botany, ethnopharmacology, biochemistry, pharmacology, pharmacokinetics and toxicity of Filifolium sibiricum (L.)Kitam

No. Chemical type Chemical component Chemical formula Isolated and identified methods Pharmacology activity References
33 Flavonoid 3,6-dimethoxyquercetagetin C17H14O8 Polyamide column chromatography Anti-bacteria, anti-oxidation [28]
34   filifolin C16H14O7 Polyamide column chromatography Anti-bacteria [28]
35   Eriodictyol C15H12O6 Polyamide column chromatography Anti-oxidation, anti-radiation, blood lipid and blood glucose lowing [28]
36   5,7,4′-Trihy-droxy-6-methoxy-flavanone   Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography Anti-depression [29]
37   4-Hydroxyacetophenone C8H8O2 Polyamide column chromatography, silica gel column chromatograph, ODS column Chromatography Cholagogue, anticorrosion [29]
38   Protoeatechuic-acid-methyl-este C8H8O4 Polyamide column chromatography, silica gel column chromatograph, ODS column Chromatography Anti-bacterial, anti-inflammatory, anti-oxidative, neuroprotective [29]
39   l-2-O-methyl-chiro-inositol   Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography Anti-hyperlipidemic [29]
40   Homoorientin C21H20O11 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-oxidation, anti-inflammation, anti-virus, anti-tumor, analgesia, neuroprotection and heart protection [30]
41   Isovitexin C21H20O10 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-bacterial, anti-viral, anti-inflammatory, liver protection [30]
42   Apigenin-6-arabinosaccharide -8-glucoside C26H28O14 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-inflammation [30]
43   Apigenin-3′-methoxy-7-O-rutin glycoside C28H32O15 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-inflammation [30]
44   Quercetin C15H10O7 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Expectorant, anti-tussive, anti-inflammation. Swelling diuresis reduction, clear heat and detoxify, immunity increasing. Blood pressure and blood lipid lowering, coronary arteriosclerosis, coronary heart disease, angina pectoris, myocardial ischemia, arrhythmia prevention [30]
45   Hyperoside C21H20O12 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-tumor, anti-oxidation, anti-depression, heart or brain ischemia protection, liver protection, immune regulation [30]
46   Isoquercitrin C21H20O12 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-hypertension, anti-depression, sedation, anti-thrombosis, anti-oxidation, anti-aging [30]
47   Isorhamnetin-3-O-glucoside C22H22O12 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-oxidation, anti-apoptosis, neuroprotection [30]
48   Isorhamnetin-3-O-rutinoside C28H32O16 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-oxidation, anti-tumor, anti-inflammatory, anti-viral, anti-allergy, cardioprotection [30]
49   Quercetin -3-O-rutin sugar -7-O-glucoside C33H38O25 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-inflammation,immunity increasing, heart protection [30]
50   Eriocitrin C27H32O15 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-oxidation, blood lipid lowering [30]
51   Eriodictyol C15H12O6 Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography Anti-oxidant [30]
52   Tricin C17H14O7 Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization Colon cancer prevention, anti-oxidation [35]
53   5,7-Dihydroxychromone C9H6O4 Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization Neuroprotection [35]
54   Capillarisin C16H12O7 Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization Anti-oxidant, anti-inflammatory and anti-tumor [35]
55   P-acetyl-phenol-beta-d-glucoside   EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC   [36]
56   4-(1-Hydroxyethyl)-phenol-1-O-β-d-glucoside   EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC   [36]
57 Triterpenoid saponin/Steroidal glycosides Daucosterol C35H60O6 Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography Anti-tumor, anti-oxidation and nerve protection [35]
58   β-Sitosterol C29H50O Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization Blood lipid lowering, anti-inflammatory,anti-bacterial, anti-oxidant, anti-tumor, antipyretic and analgesic, gastric mucosa protection,balance regulation of bone metabolism [35]
59 Coumarins Scopolin C16H18O9 EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC / [36]
60   Scopoletin C10H8O4 Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization Blood pressure lowering, blood fat reducing, anti-inflammation, anti-tumor, antipyretic [36]
61 Alkaloids Adenosine C10H13N5O4 EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC Vasodilation, treatment of heart disease [36]
62 Aromatic species Dibutyl phthalate C16H22O4 EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC   [36]
63   Diisobutyl phthalate C16H22O4 EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC   [36]
64   Phloroglucinol C6H6O3 Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography Smooth muscle relaxation, antispasticity, progesterone regulation, fetal protection [29]
65 Diphenylpyrones Mangiferin C19H18O11 EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography, UV spectrum and IR spectrum.C Anti-tumor, anti-leukemia, analgesia, antidiabetic, anti-inflammatory, cough relief, immune regulation, inhibition of lipid peroxidation [36]