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Table 1 Chemical component, isolated and identified methods and pharmacology activity on Filifoliumsibiricum (L.)Kitam

From: A comprehensive review of the botany, ethnopharmacology, biochemistry, pharmacology, pharmacokinetics and toxicity of Filifolium sibiricum (L.)Kitam

No.

Chemical type

Chemical component

Chemical formula

Isolated and identified methods

Pharmacology activity

References

33

Flavonoid

3,6-dimethoxyquercetagetin

C17H14O8

Polyamide column chromatography

Anti-bacteria, anti-oxidation

[28]

34

 

filifolin

C16H14O7

Polyamide column chromatography

Anti-bacteria

[28]

35

 

Eriodictyol

C15H12O6

Polyamide column chromatography

Anti-oxidation, anti-radiation, blood lipid and blood glucose lowing

[28]

36

 

5,7,4′-Trihy-droxy-6-methoxy-flavanone

 

Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography

Anti-depression

[29]

37

 

4-Hydroxyacetophenone

C8H8O2

Polyamide column chromatography, silica gel column chromatograph, ODS column Chromatography

Cholagogue, anticorrosion

[29]

38

 

Protoeatechuic-acid-methyl-este

C8H8O4

Polyamide column chromatography, silica gel column chromatograph, ODS column Chromatography

Anti-bacterial, anti-inflammatory, anti-oxidative, neuroprotective

[29]

39

 

l-2-O-methyl-chiro-inositol

 

Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography

Anti-hyperlipidemic

[29]

40

 

Homoorientin

C21H20O11

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-oxidation, anti-inflammation, anti-virus, anti-tumor, analgesia, neuroprotection and heart protection

[30]

41

 

Isovitexin

C21H20O10

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-bacterial, anti-viral, anti-inflammatory, liver protection

[30]

42

 

Apigenin-6-arabinosaccharide -8-glucoside

C26H28O14

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-inflammation

[30]

43

 

Apigenin-3′-methoxy-7-O-rutin glycoside

C28H32O15

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-inflammation

[30]

44

 

Quercetin

C15H10O7

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Expectorant, anti-tussive, anti-inflammation. Swelling diuresis reduction, clear heat and detoxify, immunity increasing. Blood pressure and blood lipid lowering, coronary arteriosclerosis, coronary heart disease, angina pectoris, myocardial ischemia, arrhythmia prevention

[30]

45

 

Hyperoside

C21H20O12

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-tumor, anti-oxidation, anti-depression, heart or brain ischemia protection, liver protection, immune regulation

[30]

46

 

Isoquercitrin

C21H20O12

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-hypertension, anti-depression, sedation, anti-thrombosis, anti-oxidation, anti-aging

[30]

47

 

Isorhamnetin-3-O-glucoside

C22H22O12

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-oxidation, anti-apoptosis, neuroprotection

[30]

48

 

Isorhamnetin-3-O-rutinoside

C28H32O16

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-oxidation, anti-tumor, anti-inflammatory, anti-viral, anti-allergy, cardioprotection

[30]

49

 

Quercetin -3-O-rutin sugar -7-O-glucoside

C33H38O25

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-inflammation,immunity increasing, heart protection

[30]

50

 

Eriocitrin

C27H32O15

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-oxidation, blood lipid lowering

[30]

51

 

Eriodictyol

C15H12O6

Macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography and high performance liquid chromatography

Anti-oxidant

[30]

52

 

Tricin

C17H14O7

Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization

Colon cancer prevention, anti-oxidation

[35]

53

 

5,7-Dihydroxychromone

C9H6O4

Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization

Neuroprotection

[35]

54

 

Capillarisin

C16H12O7

Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization

Anti-oxidant, anti-inflammatory and anti-tumor

[35]

55

 

P-acetyl-phenol-beta-d-glucoside

 

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

 

[36]

56

 

4-(1-Hydroxyethyl)-phenol-1-O-β-d-glucoside

 

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

 

[36]

57

Triterpenoid saponin/Steroidal glycosides

Daucosterol

C35H60O6

Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography

Anti-tumor, anti-oxidation and nerve protection

[35]

58

 

β-Sitosterol

C29H50O

Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization

Blood lipid lowering, anti-inflammatory,anti-bacterial, anti-oxidant, anti-tumor, antipyretic and analgesic, gastric mucosa protection,balance regulation of bone metabolism

[35]

59

Coumarins

Scopolin

C16H18O9

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

/

[36]

60

 

Scopoletin

C10H8O4

Extraction, silica gel column chromatography, polyamide column chromatography, recrystallization

Blood pressure lowering, blood fat reducing, anti-inflammation, anti-tumor, antipyretic

[36]

61

Alkaloids

Adenosine

C10H13N5O4

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

Vasodilation, treatment of heart disease

[36]

62

Aromatic species

Dibutyl phthalate

C16H22O4

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

 

[36]

63

 

Diisobutyl phthalate

C16H22O4

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography HPLC

 

[36]

64

 

Phloroglucinol

C6H6O3

Polyamide column chromatography, silica gel column chromatograph, ODS column chromatography

Smooth muscle relaxation, antispasticity, progesterone regulation, fetal protection

[29]

65

Diphenylpyrones

Mangiferin

C19H18O11

EtOH extract, macroporous adsorption resin column chromatography, silica gel column chromatography, ODS column chromatography, UV spectrum and IR spectrum.C

Anti-tumor, anti-leukemia, analgesia, antidiabetic, anti-inflammatory, cough relief, immune regulation, inhibition of lipid peroxidation

[36]