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Fig. 2 | Chinese Medicine

Fig. 2

From: Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa

Fig. 2

The effects of LJF on biofilm formation, motility, virulence factors and AHL production. a The dose–response curves of antibiofilm effects of LJF, Cremastrae Pseudobulbus and Forsythiae Fructus. b Growth curves of bacterial growth at different sub-MICs of LJF. c, d Swimming and swarming motility related to biofilm adhesion. eh The virulence factors related to pathogenicity (pyocyanin, alginate, elastase and rhamnolipid). i Anti-endotoxin effects. j, k Product ion mass spectrometry of C4-HSL and 3-oxo-C12-HSL(1st line), culture medium (2nd line), culture medium + C4-HSL/3-oxo-C12-HSL (3rd line) and culture supernatants of PA treated with LJF (1/16MIC, 1/4MIC and MIC) for 72 h by LC–MS/MS analysis. l. Statistics analysis of C4-HSL and 3-oxo-C12-HSL level. *P < 0.05, **P < 0.01, #P < 0.05, ##P < 0.01, compared with corresponding control

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